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mmu_circArhgap6_992

Basic information of circular RNA
PanCircBase ID:

mmu_circArhgap6_992

mm39_Chr. Position ID:

chrX|168029517|168048598|+

Gene name:

Arhgap6

Transcript:

ENSMUST00000033721.13

CircRNA type:

Exonic circular (circ)RNA

Exon/Intron count:

6

Exon/intron indexes:

4,5,6,7,8,9

Exon/intron offsets:

0,1994,7056,9964,11130,18901

Genomic length:

19081

Exon/intron sizes in nt:

26,01,96,56,15,11,49,100

Flanking exon/introns:

chrX:168020557-168029517|chrX:168048598-168064956

Splice length:

992

Other database IDs:

CIRCpedia: MMU_CIRCpedia_11754, circAtlas: mmu-Arhgap6_0001

circBase: hsa_circ_0139602, circAtlas: hsa-ARHGAP6_0004, CIRCpedia: HSA_CIRCpedia_94302

Human Ortholog IDs:
Mature spliced Sequence:

AATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCTAATGACCGGGCATATAAACTGAAGCAAGACTTGCAGAGGGAGGAGCAGAAGGATGCATCATCGGATTTTGTGTCTTCCCTCCTCCCATTTGGGAATAAAAAACAAAACAAAGAACTCTCAAGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCAAATGAGTCTACATCACCGAATACTCCAGAACCAGCTCCTCGGGCCAGGAGAAGGGGCGCCATGTCCGTGGATTCCATCACTGATCTGGATGACAACCAGTCTCGACTCCTAGAAGCTTTACAACTCTCCTTGCCTGCTGAGGCTCAGAGTAAAAAAGAAAAGGCCAGAGATAAGAAGCTGAGTCTGAATCCTATTTACAGGCAGGTCCCCAGGCTGGTGGACAGCTGCTGTCAACATCTGGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAGAAGAGAGTAAGACAATTGCGTGAAGAATTTGACCGTGGGGTTGATGTCTGTCTGGAAGAGGAGCATAGTGTTCACGATGTGGCAGCCTTGTTAAAGGAGTTCCTTAGAGACATGCCTGACCCCCTTCTCACAAGGGAGCTATACACTGCATTTATCAACACTCTCCTGTTGGAGCCTGAGGAACAACTGGGCACCTTGCAACTCCTCATTTACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTCCTACAGTTCCTCTCCATTGTGGCCAGGCATGCTGATGATAATGTCAGCAAAGATGGACAAGAGGTTACTGGGAACAAAATGACATCTCTGAACTTAGCCACTATATTTGGACCCAACCTGCTCCACAAGCAGAAGTCATCAGACAAAGAATATTCTGTTCAGAGCTCAGCCAGAGCTGAGGAGAGCACAGCCATCATAGCTGTGGTACAGAAGATGATTGAAAATTATGAAGCCTTGTTCATG

Divergent primers for circular RNA PCR

Primer Set-1

Forward primer
Tm
Reverse primer
Tm
Product size

CAGAGCTGAGGAGAGCACAG

59.83

TCCTTCTGCTCCTCCCTCTG

60.33

173

Primer Set-2

Forward primer
Tm
Reverse primer
Tm
Product size

CTGAGGAGAGCACAGCCATC

60.18

TCCTTCTGCTCCTCCCTCTG

60.33

168

PCR template sequence:

CAAAGAATATTCTGTTCAGAGCTCAGCCAGAGCTGAGGAGAGCACAGCCATCATAGCTGTGGTACAGAAGATGATTGAAAATTATGAAGCCTTGTTCATGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCTAATGACCGGGCATATAAACTGAAGCAAGACTTGCAGAGGGAGGAGCAGAAGGA

Note: Users can design additional primers for provided template sequence using Primer3 or NCBI primer-blast.
miRNAs associated with circular RNAs
No of miRNAs

12

Interacting miRNAs (#binding sites)

mmu-miR-1904(2), mmu-let-7a-5p(1), mmu-miR-7b-5p(1), mmu-let-7e-5p(1), mmu-let-7b-5p(1), mmu-let-7c-5p(1), mmu-miR-143-3p(1), mmu-miR-214-3p(1), mmu-let-7d-5p(1), mmu-miR-98-5p(1), mmu-miR-705(1), mmu-miR-207(1)

siRNAs for circular RNA silencing
Junction sequence

AGCCTTGTTCATGAATTCATCCCACA

siRNA sets

GATGAATTCATGAACAAGG,TGAATTCATGAACAAGGCT,ATGAATTCATGAACAAGGC

Protein-coding potential of circular RNAs

CPAT analysis

CPAT ORF ID
CPAT Fickett
CPAT Hexamer
Coding probabilty
ORF length

CIRCARHGAP6_992_ORF_1

0.9141

0.149306341

0.98913637

1038

ORF sequence:

ATGCCCTTATCCCAAGTCATTGCTAATGACCGGGCATATAAACTGAAGCAAGACTTGCAGAGGGAGGAGCAGAAGGATGCATCATCGGATTTTGTGTCTTCCCTCCTCCCATTTGGGAATAAAAAACAAAACAAAGAACTCTCAAGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCAAATGAGTCTACATCACCGAATACTCCAGAACCAGCTCCTCGGGCCAGGAGAAGGGGCGCCATGTCCGTGGATTCCATCACTGATCTGGATGACAACCAGTCTCGACTCCTAGAAGCTTTACAACTCTCCTTGCCTGCTGAGGCTCAGAGTAAAAAAGAAAAGGCCAGAGATAAGAAGCTGAGTCTGAATCCTATTTACAGGCAGGTCCCCAGGCTGGTGGACAGCTGCTGTCAACATCTGGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAGAAGAGAGTAAGACAATTGCGTGAAGAATTTGACCGTGGGGTTGATGTCTGTCTGGAAGAGGAGCATAGTGTTCACGATGTGGCAGCCTTGTTAAAGGAGTTCCTTAGAGACATGCCTGACCCCCTTCTCACAAGGGAGCTATACACTGCATTTATCAACACTCTCCTGTTGGAGCCTGAGGAACAACTGGGCACCTTGCAACTCCTCATTTACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTCCTACAGTTCCTCTCCATTGTGGCCAGGCATGCTGATGATAATGTCAGCAAAGATGGACAAGAGGTTACTGGGAACAAAATGACATCTCTGAACTTAGCCACTATATTTGGACCCAACCTGCTCCACAAGCAGAAGTCATCAGACAAAGAATATTCTGTTCAGAGCTCAGCCAGAGCTGAGGAGAGCACAGCCATCATAGCTGTGGTACAGAAGATGATTGAAAATTATGAAGCCTTGTTCATGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCTAATGACCGGGCATATAAACTGA

Peptide sequence:

MPLSQVIANDRAYKLKQDLQREEQKDASSDFVSSLLPFGNKKQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGVDVCLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNVSKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEYSVQSSARAEESTAIIAVVQKMIENYEALFMNSSHRHLECPYPKSLLMTGHIN

IRESfinder result

IRESfinder score

0.499257833

IRES/non IRES

non-IRES

riboCIRC information

riboCIRC ID

NA

NA

Evidence
Peptide sequence:

NA

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