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mmu_circAp2b1_488

Basic information of circular RNA
PanCircBase ID:

mmu_circAp2b1_488

mm39_Chr. Position ID:

chr11|83207245|83215582|+

Gene name:

Ap2b1

Transcript:

ENSMUST00000176944.8

CircRNA type:

Exonic circular (circ)RNA

Exon/Intron count:

3

Exon/intron indexes:

3,4,5

Exon/intron offsets:

0,5519,8091

Genomic length:

8337

Exon/intron sizes in nt:

10,61,36,246

Flanking exon/introns:

chr11:83199100-83207245|chr11:83215582-83223811

Splice length:

488

Other database IDs:

CIRCpedia: MMU_CIRCpedia_224627, circAtlas: mmu-Ap2b1_0004

circAtlas: hsa-SCAF8_0001, CIRCpedia: HSA_CIRCpedia_20234

Human Ortholog IDs:
Mature spliced Sequence:

GAGAAATTTTTGAATTAAAAGCTGAACTCAACAATGAAAAGAAAGAAAAGAGGAAGGAGGCTGTGAAGAAAGTGATTGCTGCTATGACCGTGGGGAAGGACGTGAGCTCTCTCTTCCCAGATGTGGTGAACTGCATGCAGACTGACAACCTGGAACTAAAGAAGCTCGTGTACCTCTATCTGATGAACTATGCCAAGAGTCAGCCAGACATGGCCATCATGGCTGTCAACAGCTTTGTGAAGGATTGTGAAGATCCCAATCCTTTGATTCGAGCCTTGGCAGTTAGAACCATGGGATGCATCCGGGTGGACAAGATTACAGAGTATCTCTGTGAACCCCTCCGCAAGTGCTTGAAGGATGAAGACCCCTATGTTCGGAAAACGGCAGCAGTATGCGTGGCAAAACTCCATGATATCAATGCCCAGATGGTGGAAGATCAGGGATTTCTGGATTCTCTGCGGGATCTCATAGCAGATTCAAACCCAATG

Divergent primers for circular RNA PCR

Primer Set-1

Forward primer
Tm
Reverse primer
Tm
Product size

CTGGATTCTCTGCGGGATCTC

60

CTTCCCCACGGTCATAGCAG

60.18

140

Primer Set-2

Forward primer
Tm
Reverse primer
Tm
Product size

TCTGGATTCTCTGCGGGATC

58.96

CTTCCCCACGGTCATAGCAG

60.18

141

PCR template sequence:

AGTATGCGTGGCAAAACTCCATGATATCAATGCCCAGATGGTGGAAGATCAGGGATTTCTGGATTCTCTGCGGGATCTCATAGCAGATTCAAACCCAATGGAGAAATTTTTGAATTAAAAGCTGAACTCAACAATGAAAAGAAAGAAAAGAGGAAGGAGGCTGTGAAGAAAGTGATTGCTGCTATGACCGTGGGGAAGGA

Note: Users can design additional primers for provided template sequence using Primer3 or NCBI primer-blast.
miRNAs associated with circular RNAs
No of miRNAs

6

Interacting miRNAs (#binding sites)

mmu-miR-322-5p(1), mmu-miR-15b-5p(1), mmu-miR-320-3p(1), mmu-miR-673-5p(1), mmu-miR-335-3p(1), mmu-miR-350-3p(1)

siRNAs for circular RNA silencing
Junction sequence

TTCAAACCCAATGGAGAAATTTTTGA

siRNA sets

AATTTCTCCATTGGGTTTG, AAAAATTTCTCCATTGGGT, AAAATTTCTCCATTGGGTT

Protein-coding potential of circular RNAs

CPAT analysis

CPAT ORF ID
CPAT Fickett
CPAT Hexamer
Coding probabilty
ORF length

CIRCAP2B1_488_ORF_1

1.2078

0.38907384

0.835265608

423

ORF sequence:

ATGACCGTGGGGAAGGACGTGAGCTCTCTCTTCCCAGATGTGGTGAACTGCATGCAGACTGACAACCTGGAACTAAAGAAGCTCGTGTACCTCTATCTGATGAACTATGCCAAGAGTCAGCCAGACATGGCCATCATGGCTGTCAACAGCTTTGTGAAGGATTGTGAAGATCCCAATCCTTTGATTCGAGCCTTGGCAGTTAGAACCATGGGATGCATCCGGGTGGACAAGATTACAGAGTATCTCTGTGAACCCCTCCGCAAGTGCTTGAAGGATGAAGACCCCTATGTTCGGAAAACGGCAGCAGTATGCGTGGCAAAACTCCATGATATCAATGCCCAGATGGTGGAAGATCAGGGATTTCTGGATTCTCTGCGGGATCTCATAGCAGATTCAAACCCAATGGAGAAATTTTTGAATTAA

Peptide sequence:

MTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMEKFLN

IRESfinder result

IRESfinder score

0.390300032

IRES/non IRES

non-IRES

riboCIRC information

riboCIRC ID

NA

NA

Evidence
Peptide sequence:

NA

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