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mmu_circBrwd1_616

Basic information of circular RNA
PanCircBase ID:

mmu_circBrwd1_616

mm39_Chr. Position ID:

chr16|95828544|95835093|-

Gene name:

Brwd1

Transcript:

ENSMUST00000099502.9

CircRNA type:

Exonic circular (circ)RNA

Exon/Intron count:

6

Exon/intron indexes:

29,28,27,26,25,24

Exon/intron offsets:

0,832,3290,4182,6240,6423

Genomic length:

6549

Exon/intron sizes in nt:

6,21,12,83,12,51,08,120

Flanking exon/introns:

chr16:95825076-95828544|chr16:95835093-95837061

Splice length:

616

Other database IDs:

circAtlas: mmu-Brwd1_0021

circBase: hsa_circ_0061726, circAtlas: hsa-BRWD1_0050, CIRCpedia: HSA_CIRCpedia_35523

Human Ortholog IDs:
Mature spliced Sequence:

AGTTTACGAAGGATGACTCCAGCAGAACTTGCAAATATGGAACACCTATATGAGTTTCACCCTCCTGTGTGGATAACGGACACCACACTTCGGAAGTCTCCCTTTGTTCCTCAGATGGGTGATGAGGTGATGTACTTCCGTCAGGGTCATGAAGCTTATATTGAAGCTGTCAGAAGAAATAACATTTATGAACTAAATCCTCACAAGGAGCCATGGAGGAAAATGGATCTTAGGGATCAAGAACTGGTCAAAATTGTTGGACTAAGGTATGAGGTTGGACCACCTACACTTTGTTGCCTCAAACTAGCATTTATAGATCCAGCGACTGGCAGACTGACGGATAAATCTTTCTCTATTAGATATCATGACATGCCAGATGTTATTGATTTTCTTGTGTTGCGCCAATTTTATGATGAAGCAAGACAGAGAAACTGGCAGCCTTGTGACAGATTTCGATCTATAATTGATGATGCTTGGTGGTTTGGAACCGTGTTGAGTCAAGAACCGTATCAACCCCAGTATCCTGACAGTCACTTCCAGTGTTACATTGTTAGGTGGGACAACACCGAGACTGAAAAGCTTAGCCCTTGGGACATGGAACCGATTCCTGACAATG

Divergent primers for circular RNA PCR

Primer Set-1

Forward primer
Tm
Reverse primer
Tm
Product size

GGGACAACACCGAGACTGAA

59.61

CCGAAGTGTGGTGTCCGTTA

59.97

153

Primer Set-2

Forward primer
Tm
Reverse primer
Tm
Product size

GGGACAACACCGAGACTGAA

59.61

ACTTCCGAAGTGTGGTGTCC

59.89

157

PCR template sequence:

CAGTATCCTGACAGTCACTTCCAGTGTTACATTGTTAGGTGGGACAACACCGAGACTGAAAAGCTTAGCCCTTGGGACATGGAACCGATTCCTGACAATGAGTTTACGAAGGATGACTCCAGCAGAACTTGCAAATATGGAACACCTATATGAGTTTCACCCTCCTGTGTGGATAACGGACACCACACTTCGGAAGTCTC

Note: Users can design additional primers for provided template sequence using Primer3 or NCBI primer-blast.
miRNAs associated with circular RNAs
No of miRNAs

2

Interacting miRNAs (#binding sites)

mmu-miR-125a-5p(1), mmu-miR-411-3p(1)

siRNAs for circular RNA silencing
Junction sequence

ATTCCTGACAATGAGTTTACGAAGGA

siRNA sets

TCGTAAACTCATTGTCAGG,CTTCGTAAACTCATTGTCA,TTCGTAAACTCATTGTCAG

Protein-coding potential of circular RNAs

CPAT analysis

CPAT ORF ID
CPAT Fickett
CPAT Hexamer
Coding probabilty
ORF length

CIRCBRWD1_616_ORF_1

0.9508

0.041366741

0.803213322

657

ORF sequence:

ATGACTCCAGCAGAACTTGCAAATATGGAACACCTATATGAGTTTCACCCTCCTGTGTGGATAACGGACACCACACTTCGGAAGTCTCCCTTTGTTCCTCAGATGGGTGATGAGGTGATGTACTTCCGTCAGGGTCATGAAGCTTATATTGAAGCTGTCAGAAGAAATAACATTTATGAACTAAATCCTCACAAGGAGCCATGGAGGAAAATGGATCTTAGGGATCAAGAACTGGTCAAAATTGTTGGACTAAGGTATGAGGTTGGACCACCTACACTTTGTTGCCTCAAACTAGCATTTATAGATCCAGCGACTGGCAGACTGACGGATAAATCTTTCTCTATTAGATATCATGACATGCCAGATGTTATTGATTTTCTTGTGTTGCGCCAATTTTATGATGAAGCAAGACAGAGAAACTGGCAGCCTTGTGACAGATTTCGATCTATAATTGATGATGCTTGGTGGTTTGGAACCGTGTTGAGTCAAGAACCGTATCAACCCCAGTATCCTGACAGTCACTTCCAGTGTTACATTGTTAGGTGGGACAACACCGAGACTGAAAAGCTTAGCCCTTGGGACATGGAACCGATTCCTGACAATGAGTTTACGAAGGATGACTCCAGCAGAACTTGCAAATATGGAACACCTATATGA

Peptide sequence:

MTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPHKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTETEKLSPWDMEPIPDNEFTKDDSSRTCKYGTPI

IRESfinder result

IRESfinder score

0.578158591

IRES/non IRES

IRES

riboCIRC information

riboCIRC ID

NA

NA

Evidence
Peptide sequence:

NA

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